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Ribosome Subunit Stapling for Orthogonal Translation in E. coli
The creation of orthogonal large and small ribosomal subunits, which interact with each other but not with endogenous ribosomal subunits, would extend our capacity to create new functions in the ribosome by making the large subunit evolvable. To this end, we rationally designed a ribosomal RNA that...
Autores principales: | Fried, Stephen D, Schmied, Wolfgang H, Uttamapinant, Chayasith, Chin, Jason W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678508/ https://www.ncbi.nlm.nih.gov/pubmed/26465656 http://dx.doi.org/10.1002/anie.201506311 |
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