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Odontogenic myxoma: Report of three cases and retrospective review of literature in Indian population
PURPOSE: To review the clinical pattern and treatment modalities meted out to patients of odontogenic myxoma (OM) in Indian population in last 30 years and also to report 3 cases of OM. METHOD: A retrospective review of radiograph and histopathology of three cases of odontogenic myxoma treated betwe...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678552/ https://www.ncbi.nlm.nih.gov/pubmed/26681859 http://dx.doi.org/10.4103/0976-237X.169862 |
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author | Chaudhary, Zainab Sharma, Pankaj Gupta, Shalini Mohanty, Sujata Naithani, Manish Jain, Anshul |
author_facet | Chaudhary, Zainab Sharma, Pankaj Gupta, Shalini Mohanty, Sujata Naithani, Manish Jain, Anshul |
author_sort | Chaudhary, Zainab |
collection | PubMed |
description | PURPOSE: To review the clinical pattern and treatment modalities meted out to patients of odontogenic myxoma (OM) in Indian population in last 30 years and also to report 3 cases of OM. METHOD: A retrospective review of radiograph and histopathology of three cases of odontogenic myxoma treated between 2005 and 2011 was done. Immunohistochemical analysis was performed to examine the pattern of vimentin and NSE. Also a computerized literature search using Medline and Google scholar was conducted for published articles on OM in Indian population in last 30 years. RESULT: A total of 32 OM cases reviewed from 25 articles retrieved. Out of them 24 myxomas were present in maxilla, only 8 were in mandible and a single case was present in supraglottic region (larynx). Surgical procedure carried out was excision and curettage in 16 patients and resection with safe margin followed by reconstruction 13 patients. All the three reported cases were successfully treated by tumor enucleation and peripheral ostectomy with no recurrence after 3 to 7 years. CONCLUSION: Odontogenic myxoma is a rare odontogenic tumor with inconclusive clinical and radiographic features, hence histopathological examination is mandatory to confirm its diagnosis. Although the immunohistochemical analysis may help in diagnosis but plays no role in guiding treatment planning or predicting the rate of recurrence. Currently we lack data on number of reported OM cases in Indian population as author feels more patients must have been treated then reported. |
format | Online Article Text |
id | pubmed-4678552 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-46785522015-12-17 Odontogenic myxoma: Report of three cases and retrospective review of literature in Indian population Chaudhary, Zainab Sharma, Pankaj Gupta, Shalini Mohanty, Sujata Naithani, Manish Jain, Anshul Contemp Clin Dent Original Article PURPOSE: To review the clinical pattern and treatment modalities meted out to patients of odontogenic myxoma (OM) in Indian population in last 30 years and also to report 3 cases of OM. METHOD: A retrospective review of radiograph and histopathology of three cases of odontogenic myxoma treated between 2005 and 2011 was done. Immunohistochemical analysis was performed to examine the pattern of vimentin and NSE. Also a computerized literature search using Medline and Google scholar was conducted for published articles on OM in Indian population in last 30 years. RESULT: A total of 32 OM cases reviewed from 25 articles retrieved. Out of them 24 myxomas were present in maxilla, only 8 were in mandible and a single case was present in supraglottic region (larynx). Surgical procedure carried out was excision and curettage in 16 patients and resection with safe margin followed by reconstruction 13 patients. All the three reported cases were successfully treated by tumor enucleation and peripheral ostectomy with no recurrence after 3 to 7 years. CONCLUSION: Odontogenic myxoma is a rare odontogenic tumor with inconclusive clinical and radiographic features, hence histopathological examination is mandatory to confirm its diagnosis. Although the immunohistochemical analysis may help in diagnosis but plays no role in guiding treatment planning or predicting the rate of recurrence. Currently we lack data on number of reported OM cases in Indian population as author feels more patients must have been treated then reported. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4678552/ /pubmed/26681859 http://dx.doi.org/10.4103/0976-237X.169862 Text en Copyright: © Contemporary Clinical Dentistry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Chaudhary, Zainab Sharma, Pankaj Gupta, Shalini Mohanty, Sujata Naithani, Manish Jain, Anshul Odontogenic myxoma: Report of three cases and retrospective review of literature in Indian population |
title | Odontogenic myxoma: Report of three cases and retrospective review of literature in Indian population |
title_full | Odontogenic myxoma: Report of three cases and retrospective review of literature in Indian population |
title_fullStr | Odontogenic myxoma: Report of three cases and retrospective review of literature in Indian population |
title_full_unstemmed | Odontogenic myxoma: Report of three cases and retrospective review of literature in Indian population |
title_short | Odontogenic myxoma: Report of three cases and retrospective review of literature in Indian population |
title_sort | odontogenic myxoma: report of three cases and retrospective review of literature in indian population |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678552/ https://www.ncbi.nlm.nih.gov/pubmed/26681859 http://dx.doi.org/10.4103/0976-237X.169862 |
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