Whole-transcriptome gene expression profiling in an epidermolysis bullosa simplex Dowling-Meara model keratinocyte cell line uncovered novel, potential therapeutic targets and affected pathways

BACKGROUND: To be able to develop effective therapeutics for epidermolysis bullosa simplex (EBS), it is necessary to elucidate the molecular pathomechanisms that give rise to the disease’s characteristic severe skin-blistering phenotype. RESULTS: Starting with a whole-transcriptome microarray analys...

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Detalles Bibliográficos
Autores principales: Herzog, Julia, Rid, Raphaela, Wagner, Martin, Hundsberger, Harald, Eger, Andreas, Bauer, Johann, Önder, Kamil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678661/
https://www.ncbi.nlm.nih.gov/pubmed/26666517
http://dx.doi.org/10.1186/s13104-015-1783-7

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