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Serotonin-secreting enteroendocrine cells respond via diverse mechanisms to acute and chronic changes in glucose availability

BACKGROUND: Enteroendocrine cells collectively constitute our largest endocrine tissue, with serotonin (5-HT) secreting enterochromaffin (EC) cells being the largest component (~50 %). This gut-derived 5-HT has multiple paracrine and endocrine roles. EC cells are thought to act as nutrient sensors a...

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Detalles Bibliográficos
Autores principales:	Zelkas, Leah, Raghupathi, Ravi, Lumsden, Amanda L., Martin, Alyce M., Sun, Emily, Spencer, Nick J., Young, Richard L., Keating, Damien J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678665/ https://www.ncbi.nlm.nih.gov/pubmed/26673561 http://dx.doi.org/10.1186/s12986-015-0051-0

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