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No association of IL-12p40 pro1.1 polymorphism with juvenile idiopathic arthritis

BACKGROUND: IL-12p40 plays an important role in the activation of the T-cell lines like Th17 and Th1-cells. Theses cells are crucial in the pathogenesis of juvenile idiopathic arthritis. A polymorphism in its promoter region and the genotype IL12p40 pro1.1 leads to a higher production of IL-12p40. W...

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Detalles Bibliográficos
Autores principales:	Eberhardt, Christiane S., Haas, Johannes-Peter, Girschick, Hermann, Schwarz, Tobias, Morbach, Henner, Rösen-Wolff, Angela, Foell, Dirk, Dannecker, Guenther, Schepp, Carsten, Ganser, Gerd, Honke, Nora, Eggermann, Thomas, Müller-Berghaus, Jan, Wagner, Norbert, Ohl, Kim, Tenbrock, Klaus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678695/ https://www.ncbi.nlm.nih.gov/pubmed/26667304 http://dx.doi.org/10.1186/s12969-015-0059-z

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