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Cartilage boundary lubrication synergism is mediated by hyaluronan concentration and PRG4 concentration and structure
BACKGROUND: Proteoglycan 4 (PRG4) and hyaluronan (HA) are key synovial fluid constituents that contribute synergistically to cartilage boundary lubrication; however, the effects of their concentrations as well as their structure, both of which can be altered in osteoarthritis, on this functional syn...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678696/ https://www.ncbi.nlm.nih.gov/pubmed/26666513 http://dx.doi.org/10.1186/s12891-015-0842-5 |