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Deciphering the role of interleukin-22 in metabolic alterations

Inflammatory processes and metabolic alterations are supposed to substantially interact. Recently, cumulating reports describe a profound role of interleukin(IL)-22 in this relationship. IL-22 is a particular kind of immune mediator that is produced by certain lymphocyte populations and regulates th...

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Detalles Bibliográficos
Autores principales: Sabat, Robert, Wolk, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678716/
https://www.ncbi.nlm.nih.gov/pubmed/26674616
http://dx.doi.org/10.1186/s13578-015-0060-8
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author Sabat, Robert
Wolk, Kerstin
author_facet Sabat, Robert
Wolk, Kerstin
author_sort Sabat, Robert
collection PubMed
description Inflammatory processes and metabolic alterations are supposed to substantially interact. Recently, cumulating reports describe a profound role of interleukin(IL)-22 in this relationship. IL-22 is a particular kind of immune mediator that is produced by certain lymphocyte populations and regulates the function of several tissue cells but not immune cells. So far, IL-22 was known to plays a fundamental role in the elimination of bacterial infections at border surfaces of the body and to protect tissues from damage. This research highlight article arranges the facts regarding the effects of IL-22 in the context of adiposity and metabolic alterations and postulates a new function of the immune system.
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spelling pubmed-46787162015-12-16 Deciphering the role of interleukin-22 in metabolic alterations Sabat, Robert Wolk, Kerstin Cell Biosci Research Highlight Inflammatory processes and metabolic alterations are supposed to substantially interact. Recently, cumulating reports describe a profound role of interleukin(IL)-22 in this relationship. IL-22 is a particular kind of immune mediator that is produced by certain lymphocyte populations and regulates the function of several tissue cells but not immune cells. So far, IL-22 was known to plays a fundamental role in the elimination of bacterial infections at border surfaces of the body and to protect tissues from damage. This research highlight article arranges the facts regarding the effects of IL-22 in the context of adiposity and metabolic alterations and postulates a new function of the immune system. BioMed Central 2015-12-15 /pmc/articles/PMC4678716/ /pubmed/26674616 http://dx.doi.org/10.1186/s13578-015-0060-8 Text en © Sabat and Wolk. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Highlight
Sabat, Robert
Wolk, Kerstin
Deciphering the role of interleukin-22 in metabolic alterations
title Deciphering the role of interleukin-22 in metabolic alterations
title_full Deciphering the role of interleukin-22 in metabolic alterations
title_fullStr Deciphering the role of interleukin-22 in metabolic alterations
title_full_unstemmed Deciphering the role of interleukin-22 in metabolic alterations
title_short Deciphering the role of interleukin-22 in metabolic alterations
title_sort deciphering the role of interleukin-22 in metabolic alterations
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678716/
https://www.ncbi.nlm.nih.gov/pubmed/26674616
http://dx.doi.org/10.1186/s13578-015-0060-8
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