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Different genome stability proteins underpin primed and naïve adaptation in E. coli CRISPR-Cas immunity

CRISPR-Cas is a prokaryotic immune system built from capture and integration of invader DNA into CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) loci, termed ‘Adaptation’, which is dependent on Cas1 and Cas2 proteins. In Escherichia coli, Cascade-Cas3 degrades invader DNA to effec...

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Detalles Bibliográficos
Autores principales: Ivančić-Baće, Ivana, Cass, Simon D, Wearne, Stephen J, Bolt, Edward L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678826/
https://www.ncbi.nlm.nih.gov/pubmed/26578567
http://dx.doi.org/10.1093/nar/gkv1213

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