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CRISPR interference and priming varies with individual spacer sequences

CRISPR–Cas (clustered regularly interspaced short palindromic repeats-CRISPR associated) systems allow bacteria to adapt to infection by acquiring ‘spacer’ sequences from invader DNA into genomic CRISPR loci. Cas proteins use RNAs derived from these loci to target cognate sequences for destruction t...

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Detalles Bibliográficos
Autores principales:	Xue, Chaoyou, Seetharam, Arun S., Musharova, Olga, Severinov, Konstantin, J. Brouns, Stan J., Severin, Andrew J., Sashital, Dipali G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678831/ https://www.ncbi.nlm.nih.gov/pubmed/26586800 http://dx.doi.org/10.1093/nar/gkv1259

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