Conformation-sensitive nucleoside analogues as topology-specific fluorescence turn-on probes for DNA and RNA G-quadruplexes

Development of probes that can discriminate G-quadruplex (GQ) structures and indentify efficient GQ binders on the basis of topology and nucleic acid type is highly desired to advance GQ-directed therapeutic strategies. In this context, we describe the development of minimally perturbing and environ...

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Detalles Bibliográficos
Autores principales: Tanpure, Arun A., Srivatsan, Seergazhi G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678839/
https://www.ncbi.nlm.nih.gov/pubmed/26202965
http://dx.doi.org/10.1093/nar/gkv743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678839/
https://www.ncbi.nlm.nih.gov/pubmed/26202965
http://dx.doi.org/10.1093/nar/gkv743

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