A novel method for the multiplexed target enrichment of MinION next generation sequencing libraries using PCR-generated baits

The enrichment of targeted regions within complex next generation sequencing libraries commonly uses biotinylated baits to capture the desired sequences. This method results in high read coverage over the targets and their flanking regions. Oxford Nanopore Technologies recently released an USB3.0-in...

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Detalles Bibliográficos
Autores principales: Karamitros, Timokratis, Magiorkinis, Gkikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678842/
https://www.ncbi.nlm.nih.gov/pubmed/26240383
http://dx.doi.org/10.1093/nar/gkv773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678842/
https://www.ncbi.nlm.nih.gov/pubmed/26240383
http://dx.doi.org/10.1093/nar/gkv773

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