RiboAbacus: a model trained on polyribosome images predicts ribosome density and translational efficiency from mammalian transcriptomes

Fluctuations in mRNA levels only partially contribute to determine variations in mRNA availability for translation, producing the well-known poor correlation between transcriptome and proteome data. Recent advances in microscopy now enable researchers to obtain high resolution images of ribosomes on...

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Detalles Bibliográficos
Autores principales: Lauria, Fabio, Tebaldi, Toma, Lunelli, Lorenzo, Struffi, Paolo, Gatto, Pamela, Pugliese, Andrea, Brigotti, Maurizio, Montanaro, Lorenzo, Ciribilli, Yari, Inga, Alberto, Quattrone, Alessandro, Sanguinetti, Guido, Viero, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678843/
https://www.ncbi.nlm.nih.gov/pubmed/26240374
http://dx.doi.org/10.1093/nar/gkv781

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