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Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA

The family of ten-eleven translocation (Tet) dioxygenases is widely distributed across the eukaryotic tree of life, from mammals to the amoeboflagellate Naegleria gruberi. Like mammalian Tet proteins, the Naegleria Tet-like protein, NgTet1, acts on 5-methylcytosine (5mC) and generates 5-hydroxymethy...

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Detalles Bibliográficos
Autores principales:	Hashimoto, Hideharu, Pais, June E., Dai, Nan, Corrêa, Ivan R., Zhang, Xing, Zheng, Yu, Cheng, Xiaodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678852/ https://www.ncbi.nlm.nih.gov/pubmed/26323320 http://dx.doi.org/10.1093/nar/gkv870

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