The sliding clamp tethers the endonuclease domain of MutL to DNA

The sliding clamp enhances polymerase processivity and coordinates DNA replication with other critical DNA processing events including translesion synthesis, Okazaki fragment maturation and DNA repair. The relative binding affinity of the sliding clamp for its partners determines how these processes...

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Detalles Bibliográficos
Autores principales: Pillon, Monica C., Babu, Vignesh M. P., Randall, Justin R., Cai, Jiudou, Simmons, Lyle A., Sutton, Mark D., Guarné, Alba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678855/
https://www.ncbi.nlm.nih.gov/pubmed/26384423
http://dx.doi.org/10.1093/nar/gkv918

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