Cytotoxic and mutagenic properties of O(4)-alkylthymidine lesions in Escherichia coli cells

Due to the abundant presence of alkylating agents in living cells and the environment, DNA alkylation is generally unavoidable. Among the alkylated DNA lesions, O(4)-alkylthymidine (O(4)-alkyldT) are known to be highly mutagenic and persistent in mammalian tissues. Not much is known about how the st...

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Detalles Bibliográficos
Autores principales: Wang, Pengcheng, Amato, Nicholas J., Zhai, Qianqian, Wang, Yinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678858/
https://www.ncbi.nlm.nih.gov/pubmed/26400162
http://dx.doi.org/10.1093/nar/gkv941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678858/
https://www.ncbi.nlm.nih.gov/pubmed/26400162
http://dx.doi.org/10.1093/nar/gkv941

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