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PARN deadenylase is involved in miRNA-dependent degradation of TP53 mRNA in mammalian cells

mRNA deadenylation is under the control of cis-acting regulatory elements, which include AU-rich elements (AREs) and microRNA (miRNA) targeting sites, within the 3′ untranslated region (3′ UTRs) of eukaryotic mRNAs. Deadenylases promote miRNA-induced mRNA decay through their interaction with miRNA-i...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiaokan, Devany, Emral, Murphy, Michael R., Glazman, Galina, Persaud, Mirjana, Kleiman, Frida E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678859/ https://www.ncbi.nlm.nih.gov/pubmed/26400160 http://dx.doi.org/10.1093/nar/gkv959

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