A YAP/TAZ-miR-130/301 molecular circuit exerts systems-level control of fibrosis in a network of human diseases and physiologic conditions

The molecular origins of fibrosis affecting multiple tissue beds remain incompletely defined. Previously, we delineated the critical role of the control of extracellular matrix (ECM) stiffening by the mechanosensitive microRNA-130/301 family, as activated by the YAP/TAZ co-transcription factors, in...

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Detalles Bibliográficos
Autores principales: Bertero, Thomas, Cottrill, Katherine A., Annis, Sofia, Bhat, Balkrishen, Gochuico, Bernadette R., Osorio, Juan C., Rosas, Ivan, Haley, Kathleen J., Corey, Kathleen E., Chung, Raymond T., Nelson Chau, B., Chan, Stephen Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678880/
https://www.ncbi.nlm.nih.gov/pubmed/26667495
http://dx.doi.org/10.1038/srep18277

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