Increased co-expression of genes harboring the damaging de novo mutations in Chinese schizophrenic patients during prenatal development

Schizophrenia is a heritable, heterogeneous common psychiatric disorder. In this study, we evaluated the hypothesis that de novo variants (DNVs) contribute to the pathogenesis of schizophrenia. We performed exome sequencing in Chinese patients (N = 45) with schizophrenia and their unaffected parents...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Li, Miaoxin, Yang, Zhenxing, Hu, Xun, Wu, Hei-Man, Ni, Peiyan, Ren, Hongyan, Deng, Wei, Li, Mingli, Ma, Xiaohong, Guo, Wanjun, Zhao, Liansheng, Wang, Yingcheng, Xiang, Bo, Lei, Wei, Sham, Pak C, Li, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678883/
https://www.ncbi.nlm.nih.gov/pubmed/26666178
http://dx.doi.org/10.1038/srep18209

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