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Sildenafil Therapy Normalizes the Aberrant Metabolomic Profile in the Comt(−/−) Mouse Model of Preeclampsia/Fetal Growth Restriction

Preeclampsia (PE) and fetal growth restriction (FGR) are serious complications of pregnancy, associated with greatly increased risk of maternal and perinatal morbidity and mortality. These complications are difficult to diagnose and no curative treatments are available. We hypothesized that the meta...

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Detalles Bibliográficos
Autores principales: Stanley, Joanna L., Sulek, Karolina, Andersson, Irene J., Davidge, Sandra T., Kenny, Louise C., Sibley, Colin P., Mandal, Rupasri, Wishart, David S., Broadhurst, David I., Baker, Philip N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678899/
https://www.ncbi.nlm.nih.gov/pubmed/26667607
http://dx.doi.org/10.1038/srep18241