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Lung anatomy, energy load, and ventilator-induced lung injury

BACKGROUND: High tidal volume can cause ventilator-induced lung injury (VILI), but positive end-expiratory pressure (PEEP) is thought to be protective. We aimed to find the volumetric VILI threshold and see whether PEEP is protective per se or indirectly. METHODS: In 76 pigs (22 ± 2 kg), we examined...

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Detalles Bibliográficos
Autores principales: Protti, Alessandro, Andreis, Davide T., Milesi, Marta, Iapichino, Giacomo E., Monti, Massimo, Comini, Beatrice, Pugni, Paola, Melis, Valentina, Santini, Alessandro, Dondossola, Daniele, Gatti, Stefano, Lombardi, Luciano, Votta, Emiliano, Carlesso, Eleonora, Gattinoni, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679691/
https://www.ncbi.nlm.nih.gov/pubmed/26671060
http://dx.doi.org/10.1186/s40635-015-0070-1