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Regulatory Effect of Iguratimod on the Balance of Th Subsets and Inhibition of Inflammatory Cytokines in Patients with Rheumatoid Arthritis

Objective. To expand upon the role of iguratimod (T-614) in the treatment of rheumatoid arthritis (RA), we investigated whether the Th1, Th17, follicular helper T cells (Tfh), and regulatory T cells (Treg) imbalance could be reversed by iguratimod and the clinical implications of this reversal. Meth...

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Detalles Bibliográficos
Autores principales: Xu, Yunzhi, Zhu, Qi, Song, Jinglve, Liu, Hongli, Miao, Yutong, Yang, Fan, Wang, Feiyan, Cheng, Wenjing, Xi, Yebin, Niu, Xiaoyin, He, Dongyi, Chen, Guangjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680115/
https://www.ncbi.nlm.nih.gov/pubmed/26713003
http://dx.doi.org/10.1155/2015/356040