Long-Term Overexpression of Hsp70 Does Not Protect against Cardiac Dysfunction and Adverse Remodeling in a MURC Transgenic Mouse Model with Chronic Heart Failure and Atrial Fibrillation

Previous animal studies had shown that increasing heat shock protein 70 (Hsp70) using a transgenic, gene therapy or pharmacological approach provided cardiac protection in models of acute cardiac stress. Furthermore, clinical studies had reported associations between Hsp70 levels and protection agai...

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Detalles Bibliográficos
Autores principales: Bernardo, Bianca C., Sapra, Geeta, Patterson, Natalie L., Cemerlang, Nelly, Kiriazis, Helen, Ueyama, Tomomi, Febbraio, Mark A., McMullen, Julie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680216/
https://www.ncbi.nlm.nih.gov/pubmed/26660322
http://dx.doi.org/10.1371/journal.pone.0145173

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