Tongue Epithelium Cells from shRNA Mediated Transgenic Goat Show High Resistance to Foot and Mouth Disease Virus

Foot and mouth disease induced by foot and mouth disease virus (FMDV) is severe threat to cloven-hoofed domestic animals. The gene 3Dpol in FMDV genome encodes the viral RNA polymerase, a vital element for FMDV replication. In this study, a conserved 3D-7414shRNA targeting FMDV-3Dpol gene was design...

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Detalles Bibliográficos
Autores principales: Li, Wenting, Wang, Kejun, Kang, Shimeng, Deng, Shoulong, Han, Hongbing, Lian, Ling, Lian, Zhengxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680861/
https://www.ncbi.nlm.nih.gov/pubmed/26671568
http://dx.doi.org/10.1038/srep17897

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