Cargando…

TP53 Mutational Analysis Enhances the Prognostic Accuracy of IHC4 and PAM50 Assays

IHC4 and PAM50 assays have been shown to provide additional prognostic information for patients with early breast cancer. We evaluated whether incorporating TP53 mutation analysis can further enhance their prognostic accuracy. We examined TP53 mutation and the IHC4 score in tumors of 605 patients di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Ching-Hung, Chen, I-Chiun, Huang, Chiun-Sheng, Hu, Fu-Chang, Kuo, Wen-Hung, Kuo, Kuan-Ting, Wang, Chung-Chieh, Wu, Pei-Fang, Chang, Dwan-Ying, Wang, Ming-Yang, Chang, Chin-Hao, Chen, Wei-Wu, Lu, Yen-Shen, Cheng, Ann-Lii
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680865/ https://www.ncbi.nlm.nih.gov/pubmed/26671300 http://dx.doi.org/10.1038/srep17879

Ejemplares similares

High Prevalence of the BIM Deletion Polymorphism in Young Female Breast Cancer in an East Asian Country
por: Lin, Ching-Hung, et al.
Publicado: (2015)

Plasma cell-free tumor DNA, PIK3CA and TP53 mutations predicted inferior endocrine-based treatment outcome in endocrine receptor-positive metastatic breast cancer
por: Chen, Tom Wei-Wu, et al.
Publicado: (2023)

Clinical Relevance of Liver Kinase B1(LKB1) Protein and Gene Expression in Breast Cancer
por: Chen, I-Chun, et al.
Publicado: (2016)

CYP19 Genetic Polymorphism Haplotype AASA Is Associated with a Poor Prognosis in Premenopausal Women with Lymph Node-Negative, Hormone Receptor-Positive Breast Cancer
por: Kuo, Sung-Hsin, et al.
Publicado: (2013)

The Impact of the Epigenetic Cancer Drug Azacitidine on Host Immunity: The Role of Myelosuppression, Iron Overload and tp53 Mutations in a Zebrafish Model
por: Wang, Shu-Ching, et al.
Publicado: (2019)

TP53 alterations in relapsed childhood acute lymphoblastic leukemia
por: Yu, Chih‐Hsiang, et al.
Publicado: (2019)

P53 IHC Result as a Prognostic Tool in MDS
por: Rezvani, Alireza, et al.
Publicado: (2023)

CSNK1E/CTNNB1 Are Synthetic Lethal To TP53 in Colorectal Cancer and Are Markers for Prognosis
por: Tiong, Khong-Loon, et al.
Publicado: (2014)

Outcomes and longitudinal trend of traumatic cataract wound dehiscence in patients with blunt ocular injury
por: Hou, Chiun-Ho, et al.
Publicado: (2021)

Association of annexin A10 expression with poor prognosis of intrahepatic cholangiocarcinoma
por: Shao, Yu-Yun, et al.
Publicado: (2022)

Case Report: Maintenance Nivolumab in Complete Responder After Multimodality Therapy in Metastatic Pancreatic Adenocarcinoma
por: Yang, Shih-Hung, et al.
Publicado: (2022)

Anti-HER2 antibody prolongs overall survival disproportionally more than progression-free survival in HER2-Positive metastatic breast cancer patients
por: Chen, I-Chun, et al.
Publicado: (2021)

TP53 codon 72 Gene Polymorphism Paradox in Associated with Various Carcinoma Incidences, Invasiveness and Chemotherapy Responses
por: Lin, Hung-Yu, et al.
Publicado: (2008)

Sorafenib in advanced hepatocellular carcinoma: current status and future perspectives
por: Hsu, Chih-Hung, et al.
Publicado: (2014)

An Exploratory Study for the Association of Gut Microbiome with Efficacy of Immune Checkpoint Inhibitor in Patients with Hepatocellular Carcinoma
por: Shen, Ying-Chun, et al.
Publicado: (2021)

A Joint Evaluation of Impaired Cardiac Sympathetic Responses and Malnutrition-Inflammation Cachexia for Mortality Risks in Hemodialysis Patients
por: Chang, Jia-Feng, et al.
Publicado: (2020)

Folic acid inhibits COLO-205 colon cancer cell proliferation through activating the FRα/c-SRC/ERK1/2/NFκB/TP53 pathway: in vitro and in vivo studies
por: Kuo, Chun-Ting, et al.
Publicado: (2015)

Ischemic Stroke Detection System with a Computer-Aided Diagnostic Ability Using an Unsupervised Feature Perception Enhancement Method
por: Tyan, Yeu-Sheng, et al.
Publicado: (2014)

Reproducibility and intratumoral heterogeneity of the PAM50 breast cancer assay
por: Hurson, Amber N., et al.
Publicado: (2023)

Accuracy of perceived glaucoma risk by patients in a clinical setting
por: Hou, Chiun-Ho, et al.
Publicado: (2021)

TP53 and TP53-associated genes are correlated with the prognosis of paediatric neuroblastoma
por: Wang, Haiwei, et al.
Publicado: (2022)

Circulating p-Cresyl Sulfate, Non-Hepatic Alkaline Phosphatase and Risk of Bone Fracture Events in Chronic Kidney Disease-Mineral Bone Disease
por: Chang, Jia-Feng, et al.
Publicado: (2021)

High prevalence of APOA1/C3/A4/A5 alterations in luminal breast cancers among young women in East Asia
por: Lin, Ching-Hung, et al.
Publicado: (2021)

Accuracy of p16 IHC in Classifying HPV-Driven OPSCC in Different Populations
por: Gallus, Roberto, et al.
Publicado: (2023)

Synthetic lethality between TP53 and ENDOD1
por: Tang, Zizhi, et al.
Publicado: (2022)

Combined Effects of Tanshinone IIA and an Autophagy Inhibitor on the Apoptosis of Leukemia Cells via p53, Apoptosis-Related Proteins and Oxidative Stress Pathways
por: Song, Ying-Chyi, et al.
Publicado: (2022)

Using Ballistocardiogram and Impedance Plethysmogram for Minimal Contact Measurement of Blood Pressure Based on a Body Weight-Fat Scale
por: Liu, Shing-Hong, et al.
Publicado: (2023)

Integration of Multivariate Statistical Control Chart and Machine Learning to Identify the Abnormal Process Parameters for Polylactide with Glass Fiber Composites in Injection Molding; Part I: The Processing Parameter Optimization for Multiple Qualities of Polylactide/Glass Fiber Composites in Injection Molding
por: Hsiao, Chi-Hao, et al.
Publicado: (2023)

Molecular characterization of AML‐MRC reveals TP53 mutation as an adverse prognostic factor irrespective of MRC‐defining criteria, TP53 allelic state, or TP53 variant allele frequency
por: Zhao, Davidson, et al.
Publicado: (2022)

Mitigating the Risk of t-MNs Development: TP53 or Not TP53?
por: Tesio, Melania
Publicado: (2023)

The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis
por: Leroy, Bernard, et al.
Publicado: (2013)

Chemical Constituents and Pharmacology of the Aristolochia (馬兜鈴 mădōu ling) species
por: Kuo, Ping-Chung, et al.
Publicado: (2012)

High pemetrexed sensitivity of docetaxel-resistant A549 cells is mediated by TP53 status and downregulated thymidylate synthase
por: Kuo, Wei-Ting, et al.
Publicado: (2017)

Transcriptomic alterations underlying metaplasia into specific metaplastic components in metaplastic breast carcinoma
por: Lien, Huang-Chun, et al.
Publicado: (2023)

Automatic capture management may cause unnecessary battery depletion in selective his‐bundle pacing
por: Wu, Hung‐Pin, et al.
Publicado: (2020)

Improvement in Injection Molding Quality Performance with Innovative Cyclone Mixers Used in Polypropylene with Spherical Silicon Dioxide Composites
por: Hu, Zhan-Xiang, et al.
Publicado: (2022)

Dynamic Contrast-Enhanced and Intravoxel Incoherent Motion MRI Biomarkers Are Correlated to Survival Outcome in Advanced Hepatocellular Carcinoma
por: Chen, Bang-Bin, et al.
Publicado: (2021)

Early Changes in DCE-MRI Biomarkers May Predict Survival Outcomes in Patients with Advanced Hepatocellular Carcinoma after Sorafenib Failure: Two Prospective Phase II Trials
por: Chen, Bang-Bin, et al.
Publicado: (2021)

Therapeutic Targeting of Aristolochic Acid Induced Uremic Toxin Retention, SMAD 2/3 and JNK/ERK Pathways in Tubulointerstitial Fibrosis: Nephroprotective Role of Propolis in Chronic Kidney Disease
por: Chang, Jia-Feng, et al.
Publicado: (2020)

The arsenal of TP53 mutants therapies: neoantigens and bispecific antibodies
por: Yang, Chang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0jm2kvujpdlhkonatfqnpc22g4