GFP-complementation assay to detect functional CPP and protein delivery into living cells

Efficient cargo uptake is essential for cell-penetrating peptide (CPP) therapeutics, which deliver widely diverse cargoes by exploiting natural cell processes to penetrate the cell’s membranes. Yet most current CPP activity assays are hampered by limitations in assessing uptake, including confoundin...

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Detalles Bibliográficos
Autores principales: Milech, Nadia, Longville, Brooke AC, Cunningham, Paula T, Scobie, Marie N, Bogdawa, Heique M, Winslow, Scott, Anastasas, Mark, Connor, Theresa, Ong, Ferrer, Stone, Shane R, Kerfoot, Maria, Heinrich, Tatjana, Kroeger, Karen M, Tan, Yew-Foon, Hoffmann, Katrin, Thomas, Wayne R, Watt, Paul M, Hopkins, Richard M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680871/
https://www.ncbi.nlm.nih.gov/pubmed/26671759
http://dx.doi.org/10.1038/srep18329

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