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High glucose environment inhibits cranial neural crest survival by activating excessive autophagy in the chick embryo

High glucose levels induced by maternal diabetes could lead to defects in neural crest development during embryogenesis, but the cellular mechanism is still not understood. In this study, we observed a defect in chick cranial skeleton, especially parietal bone development in the presence of high glu...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Yu, Li, Shuai, Wang, Guang, Ma, Zheng-Lai, Chuai, Manli, Cao, Liu, Yang, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680872/
https://www.ncbi.nlm.nih.gov/pubmed/26671447
http://dx.doi.org/10.1038/srep18321