Clinical utility of circulating tumor DNA for molecular assessment in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies. The genomic landscape of the PDAC genome features four frequently mutated genes (KRAS, CDKN2A, TP53, and SMAD4) and dozens of candidate driver genes altered at low frequency, including potential clinical targets. Ci...

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Detalles Bibliográficos
Autores principales: Takai, Erina, Totoki, Yasushi, Nakamura, Hiromi, Morizane, Chigusa, Nara, Satoshi, Hama, Natsuko, Suzuki, Masami, Furukawa, Eisaku, Kato, Mamoru, Hayashi, Hideyuki, Kohno, Takashi, Ueno, Hideki, Shimada, Kazuaki, Okusaka, Takuji, Nakagama, Hitoshi, Shibata, Tatsuhiro, Yachida, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680882/
https://www.ncbi.nlm.nih.gov/pubmed/26669280
http://dx.doi.org/10.1038/srep18425

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