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Nudix hydrolases degrade protein-conjugated ADP-ribose
ADP-ribosylation refers to the transfer of the ADP-ribose group from NAD(+) to target proteins post-translationally, either attached singly as mono(ADP-ribose) (MAR) or in polymeric chains as poly(ADP-ribose) (PAR). Though ADP-ribosylation is therapeutically important, investigation of this protein...
Autores principales: | Daniels, Casey M., Thirawatananond, Puchong, Ong, Shao-En, Gabelli, Sandra B., Leung, Anthony K. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680915/ https://www.ncbi.nlm.nih.gov/pubmed/26669448 http://dx.doi.org/10.1038/srep18271 |
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