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Subsite-specific contributions of different aromatic residues in the active site architecture of glycoside hydrolase family 12

The active site architecture of glycoside hydrolase (GH) is a contiguous subregion of the enzyme constituted by residues clustered in the three-dimensional space, recognizing the monomeric unit of ligand through hydrogen bonds and hydrophobic interactions. Mutations of the key residues in the active...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaomei, Wang, Shuai, Wu, Xiuyun, Liu, Shijia, Li, Dandan, Xu, Hao, Gao, Peiji, Chen, Guanjun, Wang, Lushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680936/
https://www.ncbi.nlm.nih.gov/pubmed/26670009
http://dx.doi.org/10.1038/srep18357