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Subsite-specific contributions of different aromatic residues in the active site architecture of glycoside hydrolase family 12
The active site architecture of glycoside hydrolase (GH) is a contiguous subregion of the enzyme constituted by residues clustered in the three-dimensional space, recognizing the monomeric unit of ligand through hydrogen bonds and hydrophobic interactions. Mutations of the key residues in the active...
Autores principales: | Zhang, Xiaomei, Wang, Shuai, Wu, Xiuyun, Liu, Shijia, Li, Dandan, Xu, Hao, Gao, Peiji, Chen, Guanjun, Wang, Lushan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680936/ https://www.ncbi.nlm.nih.gov/pubmed/26670009 http://dx.doi.org/10.1038/srep18357 |
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