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Sustained intraocular VEGF neutralization results in retinal neurodegeneration in the Ins2(Akita) diabetic mouse
Current therapies that target vascular endothelial growth factor (VEGF) have become a mainstream therapy for the management of diabetic macular oedema. The treatment involves monthly repeated intravitreal injections of VEGF inhibitors. VEGF is an important growth factor for many retinal cells, inclu...
Autores principales: | Hombrebueno, Jose R., Ali, Imran HA., Xu, Heping, Chen, Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680939/ https://www.ncbi.nlm.nih.gov/pubmed/26671074 http://dx.doi.org/10.1038/srep18316 |
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