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Heme oxygenase-1 attenuates cadmium-induced mitochondrial-caspase 3- dependent apoptosis in human hepatoma cell line

BACKGROUND: Cadmium (Cd) is a well known environmental and industrial toxicant causing damaging effects in numerous organs. In this study, we examined the role of heme oxygenase-1 (HO-1) in modulating the Cd-induced apoptosis in human hepatoma (HepG2) cells after 24 h exposure. METHODS: HepG2 cells...

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Detalles Bibliográficos
Autores principales: Lawal, Akeem O., Marnewick, Jeanine L., Ellis, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681021/
https://www.ncbi.nlm.nih.gov/pubmed/26670903
http://dx.doi.org/10.1186/s40360-015-0040-y