End stage renal disease patients have a skewed T cell receptor Vβ repertoire

BACKGROUND: End stage renal disease (ESRD) is associated with defective T-cell mediated immunity. A diverse T-cell receptor (TCR) Vβ repertoire is central to effective T-cell mediated immune responses to foreign antigens. In this study, the effect of ESRD on TCR Vβ repertoire was assessed. RESULTS:...

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Detalles Bibliográficos
Autores principales: Huang, Ling, Langerak, Anton W., Wolvers-Tettero, Ingrid L. M., Meijers, Ruud W. J., Baan, Carla C., Litjens, Nicolle H. R., Betjes, Michiel G. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681023/
https://www.ncbi.nlm.nih.gov/pubmed/26677394
http://dx.doi.org/10.1186/s12979-015-0055-7

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