Latent infection of myeloid progenitors by human cytomegalovirus protects cells from FAS-mediated apoptosis through the cellular IL-10/PEA-15 pathway

Latent infection of primary CD34(+) progenitor cells by human cytomegalovirus (HCMV) results in their increased survival in the face of pro-apoptotic signals. For instance, we have shown previously that primary myeloid cells are refractory to FAS-mediated killing and that cellular IL-10 (cIL-10) is...

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Detalles Bibliográficos
Autores principales: Poole, Emma, Lau, Jonathan C. H., Sinclair, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2015
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681070/
https://www.ncbi.nlm.nih.gov/pubmed/25957098
http://dx.doi.org/10.1099/vir.0.000180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681070/
https://www.ncbi.nlm.nih.gov/pubmed/25957098
http://dx.doi.org/10.1099/vir.0.000180

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