Investigation of sex-specific effects of apolipoprotein E on severity of EAE and MS

BACKGROUND: Despite pleiotropic immunomodulatory effects of apolipoprotein E (apoE) in vitro, its effects on the clinical course of experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS) are still controversial. As sex hormones modify immunomodulatory apoE functions, they may ex...

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Detalles Bibliográficos
Autores principales: Schrewe, L., Lill, C. M., Liu, T., Salmen, A., Gerdes, L. A., Guillot-Noel, L., Akkad, D. A., Blaschke, P., Graetz, C., Hoffjan, S., Kroner, A., Demir, S., Böhme, A., Rieckmann, P., ElAli, A., Hagemann, N., Hermann, D. M., Cournu-Rebeix, I., Zipp, F., Kümpfel, T., Buttmann, M., Zettl, U. K., Fontaine, B., Bertram, L., Gold, R., Chan, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681148/
https://www.ncbi.nlm.nih.gov/pubmed/26669675
http://dx.doi.org/10.1186/s12974-015-0429-y

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