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A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation

BACKGROUND: Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for many hematological conditions. Acute graft-versus-host disease (aGVHD) is a prevalent immune-mediated complication following HSCT. Current diagnostic biomarkers that correlate with aGVHD severity, progr...

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Detalles Bibliográficos
Autores principales: Paul, Dirk S., Jones, Allison, Sellar, Rob S., Mayor, Neema P., Feber, Andrew, Webster, Amy P., Afonso, Neuza, Sergeant, Ruhena, Szydlo, Richard M., Apperley, Jane F., Widschwendter, Martin, Mackinnon, Stephen, Marsh, Steven G. E., Madrigal, J. Alejandro, Rakyan, Vardhman K., Peggs, Karl S., Beck, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681168/
https://www.ncbi.nlm.nih.gov/pubmed/26669438
http://dx.doi.org/10.1186/s13073-015-0246-z