Lichen Planus Pemphigoides Presenting Preferentially Over Preexisting Scars: A Rare Instance of Isotopic Phenomenon

An 18-year-old girl presented with multiple itchy hyperpigmented papules and plaques, along with tense blisters over the lower limbs and buttocks for last 3 months. These papules, plaques, and bullae were mostly localized to preexisting scars. The histopathological findings from papule and bulla wer...

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Detalles Bibliográficos
Autores principales: Kumar, Piyush, Savant, Sushil S, Das, Anupam, Hassan, Shahid, Barman, Panchami Deb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681200/
https://www.ncbi.nlm.nih.gov/pubmed/26677275
http://dx.doi.org/10.4103/0019-5154.169133
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author Kumar, Piyush
Savant, Sushil S
Das, Anupam
Hassan, Shahid
Barman, Panchami Deb
author_facet Kumar, Piyush
Savant, Sushil S
Das, Anupam
Hassan, Shahid
Barman, Panchami Deb
author_sort Kumar, Piyush
collection PubMed
description An 18-year-old girl presented with multiple itchy hyperpigmented papules and plaques, along with tense blisters over the lower limbs and buttocks for last 3 months. These papules, plaques, and bullae were mostly localized to preexisting scars. The histopathological findings from papule and bulla were consistent with lichen planus (LP) and bullous pemphigoid, respectively. Direct immunofluorescence (DIF) of perilesional skin around bulla showed linear deposition of IgG and C3. Considering clinical, histopathological and DIF findings, diagnosis of LP pemphigoides (LPP) was made. The preferential localization of LPP lesions over preexisting scars was a very interesting finding in our case an extremely rare instance of the isotopic phenomenon.
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spelling pubmed-46812002015-12-16 Lichen Planus Pemphigoides Presenting Preferentially Over Preexisting Scars: A Rare Instance of Isotopic Phenomenon Kumar, Piyush Savant, Sushil S Das, Anupam Hassan, Shahid Barman, Panchami Deb Indian J Dermatol Case Report An 18-year-old girl presented with multiple itchy hyperpigmented papules and plaques, along with tense blisters over the lower limbs and buttocks for last 3 months. These papules, plaques, and bullae were mostly localized to preexisting scars. The histopathological findings from papule and bulla were consistent with lichen planus (LP) and bullous pemphigoid, respectively. Direct immunofluorescence (DIF) of perilesional skin around bulla showed linear deposition of IgG and C3. Considering clinical, histopathological and DIF findings, diagnosis of LP pemphigoides (LPP) was made. The preferential localization of LPP lesions over preexisting scars was a very interesting finding in our case an extremely rare instance of the isotopic phenomenon. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4681200/ /pubmed/26677275 http://dx.doi.org/10.4103/0019-5154.169133 Text en Copyright: © 2015 Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Kumar, Piyush
Savant, Sushil S
Das, Anupam
Hassan, Shahid
Barman, Panchami Deb
Lichen Planus Pemphigoides Presenting Preferentially Over Preexisting Scars: A Rare Instance of Isotopic Phenomenon
title Lichen Planus Pemphigoides Presenting Preferentially Over Preexisting Scars: A Rare Instance of Isotopic Phenomenon
title_full Lichen Planus Pemphigoides Presenting Preferentially Over Preexisting Scars: A Rare Instance of Isotopic Phenomenon
title_fullStr Lichen Planus Pemphigoides Presenting Preferentially Over Preexisting Scars: A Rare Instance of Isotopic Phenomenon
title_full_unstemmed Lichen Planus Pemphigoides Presenting Preferentially Over Preexisting Scars: A Rare Instance of Isotopic Phenomenon
title_short Lichen Planus Pemphigoides Presenting Preferentially Over Preexisting Scars: A Rare Instance of Isotopic Phenomenon
title_sort lichen planus pemphigoides presenting preferentially over preexisting scars: a rare instance of isotopic phenomenon
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681200/
https://www.ncbi.nlm.nih.gov/pubmed/26677275
http://dx.doi.org/10.4103/0019-5154.169133
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