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Preventive Anti-CD2 Treatment does not Impair Parasite Control in a Murine Toxoplasmosis Model

Targeting human CD2 with the monoclonal antibody (mAb) CB.219 reduces intestinal inflammation in a colitis model where T cells carry human CD2. Here, we asked whether this mAb has adverse effects on infection control. Mice expressing human CD2 on T cells (huCD2tg) were orally infected with Toxoplasm...

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Detalles Bibliográficos
Autores principales:	Erben, U., Pawlowski, N. N., Heimesaat, M. M., Loddenkemper, C., Doerfel, K., Spieckermann, S., Siegmund, B., Kühl, A. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Akadémiai Kiadó 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681358/ https://www.ncbi.nlm.nih.gov/pubmed/26716019 http://dx.doi.org/10.1556/1886.2015.00040

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