Inheritance of the 8.1 ancestral haplotype in recurrent pregnancy loss

Background and objectives: The 8.1 ancestral haplotype (AH) (HLA-A1, C7, B8, C4AQ0, C4B1, DR3, DQ2) is a remarkably long and conserved haplotype in the human major histocompatibility complex. It has been associated with both beneficial and detrimental effects, consistent with antagonistic pleiotropy...

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Detalles Bibliográficos
Autores principales: Kolte, Astrid M., Nielsen, Henriette S., Steffensen, Rudi, Crespi, Bernard, Christiansen, Ole B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681376/
https://www.ncbi.nlm.nih.gov/pubmed/26675299
http://dx.doi.org/10.1093/emph/eov031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681376/
https://www.ncbi.nlm.nih.gov/pubmed/26675299
http://dx.doi.org/10.1093/emph/eov031

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