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Inheritance of the 8.1 ancestral haplotype in recurrent pregnancy loss
Background and objectives: The 8.1 ancestral haplotype (AH) (HLA-A1, C7, B8, C4AQ0, C4B1, DR3, DQ2) is a remarkably long and conserved haplotype in the human major histocompatibility complex. It has been associated with both beneficial and detrimental effects, consistent with antagonistic pleiotropy...
Autores principales: | Kolte, Astrid M., Nielsen, Henriette S., Steffensen, Rudi, Crespi, Bernard, Christiansen, Ole B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681376/ https://www.ncbi.nlm.nih.gov/pubmed/26675299 http://dx.doi.org/10.1093/emph/eov031 |
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