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Oncogene Overdose: Too Much of a Bad Thing for Oncogene-Addicted Cancer Cells

Acquired resistance to targeted inhibitors remains a major, and inevitable, obstacle in the treatment of oncogene-addicted cancers. Newer-generation inhibitors may help overcome resistance mutations, and inhibitor combinations can target parallel pathways, but durable benefit to patients remains elu...

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Detalles Bibliográficos
Autores principales:	Amin, Amit Dipak, Rajan, Soumya S., Groysman, Matthew J., Pongtornpipat, Praechompoo, Schatz, Jonathan H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Libertas Academica 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681422/ https://www.ncbi.nlm.nih.gov/pubmed/26688666 http://dx.doi.org/10.4137/BIC.S29326

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