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A novel small molecule inhibitor of Candida albicans biofilm formation, filamentation and virulence with low potential for the development of resistance

BACKGROUND/OBJECTIVES: Candida albicans is the principal causative agent of candidiasis, the most common fungal infection in humans. Candidiasis represents the third-to-fourth most frequent nosocomial infection worldwide, as this normal commensal of humans causes opportunistic infections in an expan...

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Detalles Bibliográficos
Autores principales: Pierce, Christopher G, Chaturvedi, Ashok K, Lazzell, Anna L, Powell, Alexander T, Saville, Stephen P, McHardy, Stanton F, Lopez-Ribot, Jose L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681527/
https://www.ncbi.nlm.nih.gov/pubmed/26691764
http://dx.doi.org/10.1038/npjbiofilms.2015.12