Cargando…

A novel small molecule inhibitor of Candida albicans biofilm formation, filamentation and virulence with low potential for the development of resistance

BACKGROUND/OBJECTIVES: Candida albicans is the principal causative agent of candidiasis, the most common fungal infection in humans. Candidiasis represents the third-to-fourth most frequent nosocomial infection worldwide, as this normal commensal of humans causes opportunistic infections in an expan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pierce, Christopher G, Chaturvedi, Ashok K, Lazzell, Anna L, Powell, Alexander T, Saville, Stephen P, McHardy, Stanton F, Lopez-Ribot, Jose L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681527/ https://www.ncbi.nlm.nih.gov/pubmed/26691764 http://dx.doi.org/10.1038/npjbiofilms.2015.12

Ejemplares similares

Development of Anti-Virulence Approaches for Candidiasis via a Novel Series of Small-Molecule Inhibitors of Candida albicans Filamentation
por: Romo, Jesus A., et al.
Publicado: (2017)

In Vitro Characterization of a Biaryl Amide Anti-virulence Compound Targeting Candida albicans Filamentation and Biofilm Formation
por: Romo, Jesus A., et al.
Publicado: (2018)

Filamentation Is Associated with Reduced Pathogenicity of Multiple Non-albicans Candida Species
por: Banerjee, Mohua, et al.
Publicado: (2019)

Contributions of Candida albicans Dimorphism, Adhesive Interactions, and Extracellular Matrix to the Formation of Dual-Species Biofilms with Streptococcus gordonii
por: Montelongo-Jauregui, Daniel, et al.
Publicado: (2019)

Dispersion as an Important Step in the Candida albicans Biofilm Developmental Cycle
por: Uppuluri, Priya, et al.
Publicado: (2010)

The Role of Candida albicans SPT20 in Filamentation, Biofilm Formation and Pathogenesis
por: Tan, Xiaojiang, et al.
Publicado: (2014)

The Candida albicans Biofilm Matrix: Composition, Structure and Function
por: Pierce, Christopher G., et al.
Publicado: (2017)

Global Transcriptomic Analysis of the Candida albicans Response to Treatment with a Novel Inhibitor of Filamentation
por: Romo, Jesus A., et al.
Publicado: (2019)

Suppression of Fluconazole Resistant Candida albicans Biofilm Formation and Filamentation by Methylindole Derivatives
por: Lee, Jin-Hyung, et al.
Publicado: (2018)

Effect of silver nanoparticles on Candida albicans biofilms: an ultrastructural study
por: Lara, Humberto H., et al.
Publicado: (2015)

Filamentous Non-albicans Candida Species Adhere to Candida albicans and Benefit From Dual Biofilm Growth
por: Pathirana, Ruvini U., et al.
Publicado: (2019)

SAGA Complex Subunits in Candida albicans Differentially Regulate Filamentation, Invasiveness, and Biofilm Formation
por: Rashid, Saima, et al.
Publicado: (2022)

Streptococcus mutans Can Modulate Biofilm Formation and Attenuate the Virulence of Candida albicans
por: Barbosa, Júnia Oliveira, et al.
Publicado: (2016)

Roles of Candida albicans Gat2, a GATA-Type Zinc Finger Transcription Factor, in Biofilm Formation, Filamentous Growth and Virulence
por: Du, Han, et al.
Publicado: (2012)

Inhibitory effect of lactobacilli supernatants on biofilm and filamentation of Candida albicans, Candida tropicalis, and Candida parapsilosis
por: Poon, Yeuklan, et al.
Publicado: (2023)

Filament ring formation in the dimorphic yeast Candida albicans
Publicado: (1983)

The Role of Candida albicans Virulence Factors in the Formation of Multispecies Biofilms With Bacterial Periodontal Pathogens
por: Satala, Dorota, et al.
Publicado: (2022)

Associations of Rap1 with Cell Wall Integrity, Biofilm Formation, and Virulence in Candida albicans
por: Wang, Wen-Han, et al.
Publicado: (2022)

Effect of alcohols on filamentation, growth, viability and biofilm development in Candida albicans
por: Chauhan, Nitin M, et al.
Publicado: (2014)

Development of a High-Throughput Candida albicans Biofilm Chip
por: Srinivasan, Anand, et al.
Publicado: (2011)

An In Vitro Model for Candida albicans–Streptococcus gordonii Biofilms on Titanium Surfaces
por: Montelongo-Jauregui, Daniel, et al.
Publicado: (2018)

Cecropin D-derived synthetic peptides in the fight against Candida albicans cell filamentation and biofilm formation
por: Guevara-Lora, Ibeth, et al.
Publicado: (2023)

Validation of the Tetracycline Regulatable Gene Expression System for the Study of the Pathogenesis of Infectious Disease
por: Chaturvedi, Ashok K., et al.
Publicado: (2011)

Modulation of Candida albicans virulence in in vitro biofilms by oral bacteria
por: Morse, D.J., et al.
Publicado: (2019)

A Screen for Small Molecules to Target Candida albicans Biofilms
por: Lohse, Matthew B., et al.
Publicado: (2020)

Large-Scale Biochemical Profiling of the Candida albicans Biofilm Matrix: New Compositional, Structural, and Functional Insights
por: Lopez-Ribot, Jose L.
Publicado: (2014)

High-Throughput Screening of the Repurposing Hub Library to Identify Drugs with Novel Inhibitory Activity against Candida albicans and Candida auris Biofilms
por: Ajetunmobi, Olabayo H., et al.
Publicado: (2023)

Regulatory Role of Glycerol in Candida albicans Biofilm Formation
por: Desai, Jigar V., et al.
Publicado: (2013)

Influence of Bacterial Presence on Biofilm Formation of Candida albicans
por: Park, Su Jung, et al.
Publicado: (2014)

Impact of surface topography on biofilm formation by Candida albicans
por: Lagree, Katherine, et al.
Publicado: (2018)

Effects of farnesol and lyticase on the formation of Candida albicans biofilm
por: Sachivkina, Nadezhda, et al.
Publicado: (2020)

An In Vitro Model for Oral Mixed Biofilms of Candida albicans and Streptococcus gordonii in Synthetic Saliva
por: Montelongo-Jauregui, Daniel, et al.
Publicado: (2016)

Polyketide Glycosides from Bionectria ochroleuca Inhibit Candida albicans Biofilm Formation
por: Wang, Bin, et al.
Publicado: (2014)

Effect of Marine Polyunsaturated Fatty Acids on Biofilm Formation of Candida albicans and Candida dubliniensis
por: Thibane, Vuyisile S., et al.
Publicado: (2010)

Disarming Fungal Pathogens: Bacillus safensis Inhibits Virulence Factor Production and Biofilm Formation by Cryptococcus neoformans and Candida albicans
por: Mayer, François L., et al.
Publicado: (2017)

Inhibitory effect of ficin on Candida albicans biofilm formation and pre-formed biofilms
por: Yu, Jiantao, et al.
Publicado: (2022)

Biofilm Formation and Susceptibility to Amphotericin B and Fluconazole in Candida albicans
por: Zarei Mahmoudabadi, Ali, et al.
Publicado: (2014)

Purpurin Suppresses Candida albicans Biofilm Formation and Hyphal Development
por: Tsang, Paul Wai-Kei, et al.
Publicado: (2012)

Role of SFP1 in the Regulation of Candida albicans Biofilm Formation
por: Chen, Hsueh-Fen, et al.
Publicado: (2015)

Human serum inhibits adhesion and biofilm formation in Candida albicans
por: Ding, Xiurong, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_g59lgvtv6s4g6ac0qg2q20sbu0