Diterpenoids from the Roots of Salvia yunnanensis

ABSTRACT: Two new diterpenoids, salyunnanins I and J (1 and 2), together with ten analogues, were isolated from the roots of Salvia yunnanensis. The structures of the new isolates, possessing different neo-clerodane and seco-abietane diterpenoid skeletons respectively, were elucidated on the basis o...

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Detalles Bibliográficos
Autores principales: Xia, Fan, Wu, Chun-Yan, Yang, Xing-Wei, Li, Xian, Xu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681706/
https://www.ncbi.nlm.nih.gov/pubmed/26667937
http://dx.doi.org/10.1007/s13659-015-0080-4
Descripción
Sumario:ABSTRACT: Two new diterpenoids, salyunnanins I and J (1 and 2), together with ten analogues, were isolated from the roots of Salvia yunnanensis. The structures of the new isolates, possessing different neo-clerodane and seco-abietane diterpenoid skeletons respectively, were elucidated on the basis of comprehensive spectroscopic data. All of the compounds were tested for the inhibitory activities against six human tumor lines in vitro, and several ones showed moderate cytotoxic activities. GRAPHICAL ABSTRACT: [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13659-015-0080-4) contains supplementary material, which is available to authorized users.

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