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PTEN and NEDD4 in Human Breast Carcinoma

PTEN is an important tumor suppressor gene that antagonizes the oncogenic PI3K/AKT signaling pathway and has functions in the nucleus for maintaining genome integrity. Although PTEN inactivation by mutation is infrequent in breast cancer, transcript and protein levels are deficient in >25 % of ca...

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Detalles Bibliográficos
Autores principales:	Chen, Yilun, van de Vijver, Marc J., Hibshoosh, Hanina, Parsons, Ramon, Saal, Lao H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681749/ https://www.ncbi.nlm.nih.gov/pubmed/26276352 http://dx.doi.org/10.1007/s12253-015-9971-2

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