Phosphodiesterase-5 Inhibitors: Action on the Signaling Pathways of Neuroinflammation, Neurodegeneration, and Cognition

Phosphodiesterase type 5 inhibitors (PDE5-Is) have recently emerged as a potential therapeutic strategy for neuroinflammatory, neurodegenerative, and memory loss diseases. Mechanistically, PDE5-Is produce an anti-inflammatory and neuroprotection effect by increasing expression of nitric oxide syntha...

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Detalles Bibliográficos
Autores principales: Peixoto, Christina Alves, Nunes, Ana Karolina Santana, Garcia-Osta, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681825/
https://www.ncbi.nlm.nih.gov/pubmed/26770022
http://dx.doi.org/10.1155/2015/940207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681825/
https://www.ncbi.nlm.nih.gov/pubmed/26770022
http://dx.doi.org/10.1155/2015/940207

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