Praxis-induced seizures in a patient with juvenile myoclonic epilepsy: MEG-EEG coregistration study

PURPOSE: Juvenile myoclonic epilepsy (JME) is one of the most common generalized idiopathic epilepsies of childhood and adolescence. In some patients with JME, mathematical calculus and praxis may induce myoclonic seizures. METHODS: A reflex myoclonic seizure was recorded by simultaneous magnetoence...

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Detalles Bibliográficos
Autores principales: de León, Sira Carrasco-García, Niso, Guiomar, Canuet, Leonidas, Burriel-Lobo, Laura, Maestú, Fernando, Rodríguez-Magariños, María Gudín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681872/
https://www.ncbi.nlm.nih.gov/pubmed/26744699
http://dx.doi.org/10.1016/j.ebcr.2015.10.002
Descripción
Sumario:PURPOSE: Juvenile myoclonic epilepsy (JME) is one of the most common generalized idiopathic epilepsies of childhood and adolescence. In some patients with JME, mathematical calculus and praxis may induce myoclonic seizures. METHODS: A reflex myoclonic seizure was recorded by simultaneous magnetoencephalography (MEG) and electroencephalography (EEG) when a generalized spike–wave synchronous pattern at 3 Hz was observed. RESULTS: Source reconstruction localized the epileptogenic area to the right premotor frontal cortex. CONCLUSIONS: The present study demonstrates that the origin of epileptiform activity in JME can be localized in brain areas associated with the premotor frontal cortex.

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