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CTLA-4 and Autoimmunity: New Twists in the Tale

CTLA-4 has long been associated with control of autoimmunity. A recent study by Sharpe and colleagues explores this relationship in a model that enables conditional deletion of CTLA-4 in adult mice, with some surprising new conclusions.

Detalles Bibliográficos
Autor principal: Walker, Lucy S.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681878/
https://www.ncbi.nlm.nih.gov/pubmed/26596798
http://dx.doi.org/10.1016/j.it.2015.11.002