Cellular Adaptation to VEGF-Targeted Antiangiogenic Therapy Induces Evasive Resistance by Overproduction of Alternative Endothelial Cell Growth Factors in Renal Cell Carcinoma()()

Vascular endothelial growth factor (VEGF)–targeted antiangiogenic therapy significantly inhibits the growth of clear cell renal cell carcinoma (RCC). Eventually, therapy resistance develops in even the most responsive cases, but the mechanisms of resistance remain unclear. Herein, we developed two t...

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Detalles Bibliográficos
Autores principales: Han, Kyung Seok, Raven, Peter A., Frees, Sebastian, Gust, Kilian, Fazli, Ladan, Ettinger, Susan, Hong, Sung Joon, Kollmannsberger, Cristian, Gleave, Martin E., So, Alan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681895/
https://www.ncbi.nlm.nih.gov/pubmed/26678908
http://dx.doi.org/10.1016/j.neo.2015.11.001

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