Cargando…
A Combination of Human Embryonic Stem Cell-Derived Pancreatic Endoderm Transplant with LDHA-Repressing miRNA Can Attenuate High-Fat Diet Induced Type II Diabetes in Mice
Type II diabetes mellitus (T2D) is a chronic metabolic disorder that results from defects in both insulin secretion and insulin action. The deficit and dysfunction of insulin secreting β-cell are signature symptom for T2D. Additionally, in pancreatic β-cell, a small group of genes which are abundant...
Autores principales: | Chen, Yunya, Wang, Xiujie, Shao, Xinyu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681983/ https://www.ncbi.nlm.nih.gov/pubmed/26770982 http://dx.doi.org/10.1155/2015/796912 |
Ejemplares similares
-
Characteristics of the Endoderm: Embryonic and Extraembryonic in Mouse
por: Familari, Mary
Publicado: (2006) -
Concerted cell divisions in embryonic visceral endoderm guide anterior visceral endoderm migration
por: Antonica, Francesco, et al.
Publicado: (2019) -
Human Embryonic and Rat Adult Stem Cells with Primitive Endoderm-Like Phenotype Can Be Fated to Definitive Endoderm, and Finally Hepatocyte-Like Cells
por: Roelandt, Philip, et al.
Publicado: (2010) -
MiR-638 Repressed Vascular Smooth Muscle Cell Glycolysis by Targeting LDHA
por: Chen, Shiyuan, et al.
Publicado: (2019) -
ZFP281 recruits polycomb repressive complex 2 to restrict extraembryonic endoderm potential in safeguarding embryonic stem cell pluripotency
por: Huang, Xin, et al.
Publicado: (2020)